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Full Moon BioSystems phospho-specific protein microarray pex100
Differential expression of phospho-specific protein between cells in the pH 7.5 and pH 6.5 groups. (A) Original images of phosphorylated protein chips by SureScan Dx <t>Microarray</t> Scanner from two groups. (B) Phosphorylation sites (582) of all (432) screened proteins based on a phospho-specific protein microarray analysis. (C) KEGG enrichment analysis of proteins in the phospho-specific protein microarray according to cellular component, biological process, and molecular function. (D) Heat map representing the fold change in the expression of different phosphorylated sites of proteins in the PI3K/Akt/mTOR signaling pathway (fold change Phos/Unphos ≥ 1.6).
Phospho Specific Protein Microarray Pex100, supplied by Full Moon BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phospho-specific+protein+microarray/phospho+explorer+antibody+array/pmc06962105-67-3-7
Average 90 stars, based on 1 article reviews
phospho-specific protein microarray pex100 - by Bioz Stars, 2026-10
90/100 stars

Images

1) Product Images from "Acidic Microenvironment Regulates the Severity of Hepatic Ischemia/Reperfusion Injury by Modulating the Generation and Function of Tregs via the PI3K-mTOR Pathway"

Article Title: Acidic Microenvironment Regulates the Severity of Hepatic Ischemia/Reperfusion Injury by Modulating the Generation and Function of Tregs via the PI3K-mTOR Pathway

Journal: Frontiers in Immunology

doi: 10.3389/fimmu.2019.02945

Differential expression of phospho-specific protein between cells in the pH 7.5 and pH 6.5 groups. (A) Original images of phosphorylated protein chips by SureScan Dx Microarray Scanner from two groups. (B) Phosphorylation sites (582) of all (432) screened proteins based on a phospho-specific protein microarray analysis. (C) KEGG enrichment analysis of proteins in the phospho-specific protein microarray according to cellular component, biological process, and molecular function. (D) Heat map representing the fold change in the expression of different phosphorylated sites of proteins in the PI3K/Akt/mTOR signaling pathway (fold change Phos/Unphos ≥ 1.6).
Figure Legend Snippet: Differential expression of phospho-specific protein between cells in the pH 7.5 and pH 6.5 groups. (A) Original images of phosphorylated protein chips by SureScan Dx Microarray Scanner from two groups. (B) Phosphorylation sites (582) of all (432) screened proteins based on a phospho-specific protein microarray analysis. (C) KEGG enrichment analysis of proteins in the phospho-specific protein microarray according to cellular component, biological process, and molecular function. (D) Heat map representing the fold change in the expression of different phosphorylated sites of proteins in the PI3K/Akt/mTOR signaling pathway (fold change Phos/Unphos ≥ 1.6).

Techniques Used: Quantitative Proteomics, Microarray, Phospho-proteomics, Expressing

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Article Snippet: Expansion of CD4+CD25+ regulatory T cells (Tregs) in tumor microenvironment was one of the mechanisms by which cancer cells escaped host defense.. Thymic stromal lymphopoietin (TSLP) contributes to the generation of natural Tregs in thymus.. Therefore, the purpose of this report was to investigate the role of TSLP in the increasing prevalence of Tregs in lung cancer microenvironment.

Article Title: LKB1 is Necessary for Akt-mediated Phosphorylation of Pro-apoptotic Proteins
Article Snippet: Phospho-specific Protein Microarray was obtained from Full Moon Biosystems, Inc.

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Article Title: The Glycolytic Inhibitor 2-Deoxyglucose Activates Multiple Prosurvival Pathways through IGF1R
Article Snippet: A phospho-specific protein microarray was obtained from Full Moon Biosystems, Inc.

Article Title: LKB1 is Necessary for Akt-mediated Phosphorylation of Pro-apoptotic Proteins
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Activation Assay:

Article Title: Increased prevalence of regulatory T cells in the lung cancer microenvironment: a role of thymic stromal lymphopoietin.
Article Snippet: Expansion of CD4+CD25+ regulatory T cells (Tregs) in tumor microenvironment was one of the mechanisms by which cancer cells escaped host defense.. Thymic stromal lymphopoietin (TSLP) contributes to the generation of natural Tregs in thymus.. Therefore, the purpose of this report was to investigate the role of TSLP in the increasing prevalence of Tregs in lung cancer microenvironment.

Article Title: LKB1 is Necessary for Akt-mediated Phosphorylation of Pro-apoptotic Proteins
Article Snippet: Phospho-specific Protein Microarray was obtained from Full Moon Biosystems, Inc.

Article Title: The Glycolytic Inhibitor 2-Deoxyglucose Activates Multiple Prosurvival Pathways through IGF1R
Article Snippet: Phospho-specific Protein Microarray Analysis A phospho-specific protein microarray was obtained from Full Moon Biosystems, Inc.

Article Title: Increased prevalence of regulatory T cells in the lung cancer microenvironment: a role of thymic stromal lymphopoietin
Article Snippet: Phospho-specific protein microarray analysis The activation status of JAK/STAT pathway in TSLP-DCs, LPS-DCs, and imDCs was analyzed using phospho-specific protein microarray (Full Moon Biosystems, Inc., CA, USA).

Article Title: Increased prevalence of regulatory T cells in the lung cancer microenvironment: a role of thymic stromal lymphopoietin
Article Snippet: The activation status of JAK/STAT pathway in TSLP-DCs, LPS-DCs, and imDCs was analyzed using phospho-specific protein microarray (Full Moon Biosystems, Inc., CA, USA).

Article Title: Intracellular osteopontin negatively regulates toll-like receptor 4-mediated inflammatory response via regulating GSK3β and 4EBP1 phosphorylation.
Article Snippet: Toll-like receptors (TLRs) play an important role in host defense against invading pathogens.. By initiating a signal transduction cascade, TLRs lead to the release of pro-inflammatory cytokines.. However, the inappropriate activation of TLR signaling could result in inflammatory disorders or autoimmune diseases.

Article Title: The Glycolytic Inhibitor 2-Deoxyglucose Activates Multiple Prosurvival Pathways through IGF1R
Article Snippet: A phospho-specific protein microarray was obtained from Full Moon Biosystems, Inc.

Article Title: LKB1 is Necessary for Akt-mediated Phosphorylation of Pro-apoptotic Proteins
Article Snippet: Phospho-specific Protein Microarray analysis Phospho-specific Protein Microarray was obtained from Full Moon Biosystems, Inc.



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Differential expression of phospho-specific protein between cells in the pH 7.5 and pH 6.5 groups. (A) Original images of phosphorylated protein chips by SureScan Dx <t>Microarray</t> Scanner from two groups. (B) Phosphorylation sites (582) of all (432) screened proteins based on a phospho-specific protein microarray analysis. (C) KEGG enrichment analysis of proteins in the phospho-specific protein microarray according to cellular component, biological process, and molecular function. (D) Heat map representing the fold change in the expression of different phosphorylated sites of proteins in the PI3K/Akt/mTOR signaling pathway (fold change Phos/Unphos ≥ 1.6).
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Differential expression of phospho-specific protein between cells in the pH 7.5 and pH 6.5 groups. (A) Original images of phosphorylated protein chips by SureScan Dx <t>Microarray</t> Scanner from two groups. (B) Phosphorylation sites (582) of all (432) screened proteins based on a phospho-specific protein microarray analysis. (C) KEGG enrichment analysis of proteins in the phospho-specific protein microarray according to cellular component, biological process, and molecular function. (D) Heat map representing the fold change in the expression of different phosphorylated sites of proteins in the PI3K/Akt/mTOR signaling pathway (fold change Phos/Unphos ≥ 1.6).
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Differential expression of phospho-specific protein between cells in the pH 7.5 and pH 6.5 groups. (A) Original images of phosphorylated protein chips by SureScan Dx <t>Microarray</t> Scanner from two groups. (B) Phosphorylation sites (582) of all (432) screened proteins based on a phospho-specific protein microarray analysis. (C) KEGG enrichment analysis of proteins in the phospho-specific protein microarray according to cellular component, biological process, and molecular function. (D) Heat map representing the fold change in the expression of different phosphorylated sites of proteins in the PI3K/Akt/mTOR signaling pathway (fold change Phos/Unphos ≥ 1.6).
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Image Search Results


Differential expression of phospho-specific protein between cells in the pH 7.5 and pH 6.5 groups. (A) Original images of phosphorylated protein chips by SureScan Dx Microarray Scanner from two groups. (B) Phosphorylation sites (582) of all (432) screened proteins based on a phospho-specific protein microarray analysis. (C) KEGG enrichment analysis of proteins in the phospho-specific protein microarray according to cellular component, biological process, and molecular function. (D) Heat map representing the fold change in the expression of different phosphorylated sites of proteins in the PI3K/Akt/mTOR signaling pathway (fold change Phos/Unphos ≥ 1.6).

Journal: Frontiers in Immunology

Article Title: Acidic Microenvironment Regulates the Severity of Hepatic Ischemia/Reperfusion Injury by Modulating the Generation and Function of Tregs via the PI3K-mTOR Pathway

doi: 10.3389/fimmu.2019.02945

Figure Lengend Snippet: Differential expression of phospho-specific protein between cells in the pH 7.5 and pH 6.5 groups. (A) Original images of phosphorylated protein chips by SureScan Dx Microarray Scanner from two groups. (B) Phosphorylation sites (582) of all (432) screened proteins based on a phospho-specific protein microarray analysis. (C) KEGG enrichment analysis of proteins in the phospho-specific protein microarray according to cellular component, biological process, and molecular function. (D) Heat map representing the fold change in the expression of different phosphorylated sites of proteins in the PI3K/Akt/mTOR signaling pathway (fold change Phos/Unphos ≥ 1.6).

Article Snippet: We used a phospho-specific protein microarray (PEX100, Full Moon BioSystems, USA) containing 1,318 antibodies against 584 phosphorylation sites of 432 proteins for phosphorylation profiling.

Techniques: Quantitative Proteomics, Microarray, Phospho-proteomics, Expressing

Effect of Lem4 on tyrosine phosphorylation of signal proteins in HEK293T cell line, as detected by tyrosine phosphorylation ProArray (Full Moon BioSystems). Phosphorylation levels were increased by at least 30% at 30 sites and decreased by at least 30% at four sites in the cells overexpressing Lem4-GFP. Red dashed line indicates the level of phosphorylation in the control GFP-expressing cell line.

Journal: The Journal of Biological Chemistry

Article Title: Legionella pneumophila effector Lem4 is a membrane-associated protein tyrosine phosphatase

doi: 10.1074/jbc.RA118.003845

Figure Lengend Snippet: Effect of Lem4 on tyrosine phosphorylation of signal proteins in HEK293T cell line, as detected by tyrosine phosphorylation ProArray (Full Moon BioSystems). Phosphorylation levels were increased by at least 30% at 30 sites and decreased by at least 30% at four sites in the cells overexpressing Lem4-GFP. Red dashed line indicates the level of phosphorylation in the control GFP-expressing cell line.

Article Snippet: Phospho-specific protein microarray analysis Tyrosine phosphorylation ProArray was purchased from Full Moon Biosystems (Sunnyvale, CA).

Techniques: Phospho-proteomics, Control, Expressing